CD40LG and diabetes mellitus: However, there was evidence of effect modification by diabetes status for all four IgM OSE, with significant interaction tests (IgM MDA-LDL P interaction = 0.001, IgM MDA-P1 mimotope P interaction =0.026, IgM PC-BSA P interaction = 0.022, IgM apoB-IC P interaction = 0.002 (Fig. 1, Fig. 2, Fig. 3, Fig. 4).