We next retested the 21 mAbs from the QPLC21 biochip in along with 6 cancer biomarkers (cancer antigen 125 [CA125], carcinoembryonic antigen [CEA], cyfra 21 to 1 [CYFRA], tissue polypeptide antigen [TPAM], C-reactive protein [CRP] and human epididymis protein 4 [HE4]) on a matched sample cohort to reduce the number of variables. Here, MUC16 is linked to cancer.