TP53 and colorectal carcinoma: First, we analysed cell viability of CRC cell lines after treatment with H2O2 and determined IC50 values of 92.61, 48.35, and 61.52 μM for p53-proficient HCT116 cells, p53-deficient HCT116 cells, and SW620 cells, which express mutant p53, respectively (Figs. S8A and S8B).