EZH2 is thought to drive tumorigenesis and progression in ovarian cancer through repression of tumor suppressor genes by promoting trimethylation of histone H3K27 (H3K27me3) in the promoter regions, with the expression level of EZH2 being positively correlated with the H3K27me3 level, as Sun et al. reported [11]. The gene discussed is EZH2; the disease is ovarian cancer.