To expand these findings to the pancreas setting, we took advantage of gene expression data from cancer cell lines (iKrasC) and xenograft tumours (iKrasT) derived from an inducible genetically engineered mouse (GEM) model of Kras-driven PDAC in which doxycycline administration activates expression of a mut Kras allele [43] (Fig. 3C). This evidence concerns the gene KRAS and cancer.