The median age of the 26 converted patients was 56.4 years (range: 28 to 76 years); All patients had hepatitis B virus (HBV) infection, 16 patients (61.5%) had AFP over 400 ng/ml, 25 patients (96.2%) had Child-Pugh A liver function; the tumors of 16 patients (61.5%) were solitary; 19 patients (73.1%) were Barcelona Clinic Liver Cancer (BCLC) C stage. The gene discussed is AFP; the disease is liver cancer.