Healthy subjects had higher levels of galectin-10, CD24, CD197, CD196, CD25 and CD45RO and patients with type 1 diabetes had higher levels of CD16, CD45RA, CD274, HLA-DR, CD28, Interleukin (IL)-5R, and CD38 (Fig. 4B). This evidence concerns the gene CD274 and type 1 diabetes mellitus.