BNC2 and malaria: Among those, we found BNC2 identified with the iHS in NAE (Supplementary Table S5) as well as in Toscani and two North Eastern Italian populations52, which has been associated with facial pigmentation53; and PTPRD which we detected in NA when compared to CEU (with FST and XP-EHH; Supplementary Table S2) and has been previously described under positive selection in all the Italian populations explored by Cocca et al.52, although with signals on different markers, as well as in several malaria endemic regions of Asia54.