Rate of growth correlated positively with insulin (Spearman R = 0.42, P = 0.018) and insulin resistance measured by HOMA-IR (Spearman R = 0.40, P = 0.025), and negatively with HDL-C (Spearman R = −0.68, P = 0.74 E−05) (Fig. 3d–f), and after Bonferroni-correction for multiple-testing the negative correlation between rate of growth and HDL-C remained significant (P = 0.74 E−04). Here, INS is linked to Insulin resistance.