RAD51 and neoplasm: Interestingly, DDR genes were more enriched in drivers compared with non-drivers in all PARPi-resistant tumor groups, with the exception of drivers that were derived from copy-number alterations in RAD51-negative KB1P(M) tumors (Figures S4B–S4D), supporting the previous findings that DDR pathways are strongly involved in governing PARPi response.7