In acute kidney injury models, ischemia preconditioning activates Fundc1‐mediated mitophagy and reduces inflammation and kidney damage caused by ischemia–reperfusion injury; ischemia–reperfusion in Fundc1‐knockout mice leads to Drp1‐dependent excessive mitochondrial fission, mitochondrial dysfunction, and severe tubular cell death.39 Here, FUNDC1 is linked to acute kidney injury.