MNX1 and uterine corpus leiomyoma: It has been suggested that the association of OEIS with homeobox genes such as homeobox HB9 and retinoic acid and its receptors.1 In one of the study reported OEIS in sib from separate pregnancies concluding autosomal recessive inheritance, multifactorial, gonadal mosaicism for a dominant mutation, environmental factors.3 Association of OEIS with deletion of chromosome 1p36 has been reported.4 OEIS has also been reported in association with maternal exposure to diazepam, cigarette smoking, maternal obesity, and uterine fibroids.3,4