SHBG and cancer: The HMGCR genetic instrument identified cancer‐related biomarker associations between lower LDL‐C and lower sex hormone‐binding globulin (SHBG) (beta in nmol/L per 1 mg/dL decrease in LDL‐C −0.11, 95% CI −0.14, −0.08) and slightly lower testosterone (beta in pmol/L per 1 mg/dL decrease in LDL‐C −10.68, 95% CI −14.33, −7.04), while the PCSK9 instrument was associated with lower IGF‐1.