METTL3 and breast carcinoma: No increases in METTL3, METTL14 and WTAP protein levels were detected in VIRMA FL-transduced HS578T cells that already express high levels of endogenous full-length VIRMA (Fig. 2B) or in breast cancer cells overexpressing VIRMA N-term compared to control cells (Fig. 4C, S4J).