CCL2 and cancer: Regarding the effect on cancer cell proliferation, Dutta et al. reported that CCL2 did not increase cell proliferation in either CCL2low or CCL2high BC cells but upregulated the phosphorylation of MAP kinase (p42/p44) and increased cell invasion in various BC cells, including MCF-7, MDA-MB-436 and MDA-MB-468 cells.