CSF1 and breast cancer: Colony-stimulating factor-1 (CSF-1), also known as macrophage colony-stimulating factor (M-CSF), is the major growth factor for the mononuclear phagocytic lineage [79], and overexpression of CSF-1 and CSF-1R was found in a large percentage of BC cases in which its expression was correlated with poor prognosis [80].