CCL2 and neoplasm: The proportions of CD11b+ and CD11b+Gr1+ cells (defined as MDSCs) in the primary tumor were decreased in both Ccl2-/- and Ccr2-/- mice, but there were no significant differences in the ratio of CD4+, CD8+, or γδ T cells, B cells, CD11c+ cells, natural killer (NK), or NKT cells observed.