Bonapace et al. investigated the effect of CCL2 neutralization on tumor growth and metastasis in syngeneic mouse transplantation models, including 4T1, 4T1.2 (BALB/c), and J110 (derived from FVB-MMTV-AIB1 mouse tumor [105] and Met-1 cells [83]), producing similar levels of CCL2. Here, CCL2 is linked to neoplasm.