Thus, the depletion of Glut1 can improve the effects of RT by shortening the lifespan of TANs and enhancing neutrophil turnover, indicating that younger neutrophils have fewer opportunities to acquire markers such as PD-1 than older neutrophils and can attack tumor cells to overcome RT resistance.156 This trait makes RT-recruited neutrophils (RT-Ns) a useful tool for delivering drugs such as albumin-bound paclitaxel. The gene discussed is PDCD1; the disease is neoplasm.