Conventional type I dendritic cells (CD103+cDC1) cross-presented antigens on MHC class I to CD8+ T cells, recruited T cells to the tumor by producing CXCL9 and CXCL10 and produced IL-12 after sensing IFN-γ released from T cells,59,60 leading to the initiation and maintenance of antitumor immunity and increasing antitumor immunity in a mouse model, while CD11b+ cDC2s specifically primed CD4+ T cells and were heterogeneous.61,62 mregDCs are a recently discovered subtype of DCs. This evidence concerns the gene CD4 and neoplasm.