Between SCD1 and SOAT1, we found that SCD1 expression level is positively correlated with a cancer stemness signature20 and poor prognosis in GC patients treated with chemotherapy, thereby suggesting SCD1 to be a more interesting and likely downstream effector of ADAR1 to promote cancer stemness and chemoresistance (Supplementary Fig. 10). This evidence concerns the gene SOAT1 and gastric cancer.