Since we observed a much higher expression of p110 ADAR1 in our gastric cancer organoid lines (ratio of p150 ADAR1 to p110 ADAR1 < 0.1, Fig. 1f), we decided to first focus on the function of p110 ADAR1 isoform in governing resistant to 5FU + CDDP. Here, ADAR is linked to gastric cancer.