In the latest published article, ACKR1+ ECs (Endothelial cells) highly engaged in leukocyte recruitment into orbital connective tissue (OCT) in (thyroid-associated ophthalmopathy) TAO and that the recruitment process may be influenced by the interaction of CXCL8/ACKR1 (50). The gene discussed is ACKR1; the disease is thromboangiitis obliterans.