Cluster 2 (green) focused on basic research on the pathological mechanisms of ITP, including keywords such as “T cell subset,” “Treg cell,” “Th17 cell,” “interleukin,” “DNA methylation,” “apoptosis,” etc. Cluster 3 (blue) primarily referred to the management of ITP as evidenced by keywords “glucocorticoids,” “rituximab,” “spleen tyrosine kinase,” “splenectomy,” “eltrombopag,” etc. The last cluster (yellow) was small and only included a few keywords, such as “splenectomy.” Here, SYK is linked to autoimmune thrombocytopenic purpura.