A protein–protein interaction network was mapped showing proteins in C. parvum/MR compared with Sham/MR ilea that were upregulated including neutrophil extracellular trap formation pathway with MPO, rac family small GTPase 2 (RAC2), and IQ motif containing GTPase-activating protein 2 (IQGAP2) functionally clustered together (Figure 4D; Supplementary Figure S2B, and Supplementary Table S2). The gene discussed is IQGAP2; the disease is miotic rate.