BRCA2 and breast cancer: The target population for breast cancer awareness are women over 40 years of age, since breast cancer incidence rate increases with age, hereditary breast, and ovarian cancer syndrome, BRCA2 – germline mutations, and female sex hormones fluctuations from 60 cases per 100,000 in women 30-40 years of age to an average of 430 cases per 100,000 in women 65-75 years of age (4).