Compared with patients without significant liver fibrosis (S0–S1), patients with significant liver fibrosis (S2–S4) also had upregulated expression of CYFIP1, DCP2, EIF4E3, and IFIT5, while downregulated expression of NUDT16 and NUDT4 (Figure 7(c)). Here, NUDT4 is linked to Hepatic fibrosis.