CD8A and infection: However, throughout these studies of asymptomatic infection, there was no evidence of the CD8+ T lymphocytosis that characterises the blood picture in IM; in the first study, TCR Vβ screening could not detect obvious T‐cell clonal expansions of the kind seen in IM,125 whilst the later work used staining with HLA‐peptide tetramers to show that there were indeed activated EBV‐specific CD8+ T cells in the blood but their expansion was much more limited than in acute IM.58