IL10 and neoplasm: In AOM/IL10−/− or ApcMin/+ mouse models with chemo-induced tumor, infection with colibactin-producing E. coli strains induced an acceleration of tumor development compared to uninfected control mice or mice infected with a non-colibactin-producing mutant of these strains, or animals infected and treated with molecules inhibiting colibactin synthesis [139,142,144,153].