CCL20 and colorectal carcinoma: ETBF promotes CRC progression by secreting particles that stimulate colonic epithelial cells to produce exosome-like nanoparticles containing high levels of sphingosine-1-phosphate, CCL20, and prostaglandin E2 (PGE2) that are required for recruitment of Th17 cells into CRC tissues to support their growth and survival [131].