MMP9 and ischemic stroke: However, one of those meta-analyses showed a significant relationship between the recessive model of the MMP-9-1562C/T polymorphism (TT vs. CC + CT) and the risk of ischemic stroke in the European population (OR 2.06; 95% CI 1.14–3.73; p-value = 0.02) (Misra et al., 2018).