Surprisingly, 8 Gy × 1f‐2 Gy × 10f and 2 Gy × 15f both increased MDSCs (CD11b+Gr‐1+) in the spleen, which may be related to the weaker effects of tumor control in these two groups by using conventional fractionated RT (Figure 2G–I). This evidence concerns the gene ITGAM and neoplasm.