Although, CD3+ cells, CD4+ T cells, CD8+ T cells in rIL‐1α treated group were not higher compared to saline and Blank_CPH:SA MPs, there were significantly higher IFNγ+ CD8+ T cells (Figure 7e), which explains the observed anti‐tumor response in rIL‐1α treated mice. This evidence concerns the gene CD8A and neoplasm.