An apolipoprotein B derived peptide, ApoB29 mer peptide, is a ligand that binds with high affinity to LDLRs and was used in a study by Seo et al.76The study showed that ApoB29‐conjugated gold NPs penetrated the BBB more efficiently compared to bare gold NPs and preferentially accumulated in the tumor microenvironment (TME), demonstrating the potential of ApoB29 mer peptide as a ligand to increase NP specificity for GBM tumor cells. This evidence concerns the gene APOB and neoplasm.