Search strategy 2: To explore the effect of LDN on inflammatory biomarkers among individuals with a diagnosis of fibromyalgia: [fibromyalgia] AND [naltrexone] AND [cytokine OR cytokines OR “cytokine signatures” OR “inflammatory cytokines” OR “inflammatory markers” OR CRP OR “c-reactive protein” OR ESR OR “erythrocyte sedimentation rate” OR “plasma viscosity”]. Here, CRP is linked to fibromyalgia.