The mean IBD-KID2 scores for each group in each country were calculated and compared using an ANOVA, which showed there were no significant score differences between locations for any participant groups: children with IBD (P = 0.423), mothers (P = 0.427), fathers (P = 0.063), or siblings (P = 0.242) (Fig. 2). This evidence concerns the gene ZNF354B and inflammatory bowel disease.