AKT1 and dermatitis: Abnormal secretion or improper use of glucocorticoids, unbalance of RAAS, androgen secretion dysfunction and treatment of catecholamines will regulate the expression of intracellular inflammatory factors through regulating MAPK, PI3K/AKT/mTOR, JAK/STAT, and cAMP/PKA signaling pathways, resulting in skin inflammation.