The correlations of the C6T Aβ and F9T tau variants with long-term cognitive deficits in the TBI mice, along with their presence in sera samples from human TBI cases [55], and sera samples from human post-mortem and longitudinal AD cases [6, 56, 57], suggest that there is a common pathogenesis in all of these cases. This evidence concerns the gene MAPT and Alzheimer disease.