As IL-12 and IL-18 can induce IFN-γ from NK cells or previously stimulated T cells, we queried their role in induction of IFN-γ by MCMV, but did not find any effect of blocking IL-12 and IL-18 together in the time period before challenge on protection from P. chabaudi parasitemia or pathology by the MCMV vector (S5 Fig). This evidence concerns the gene IL18 and parasitic infectious disease.