While this is clearly a non-specific effect, as there is no B5 epitope here, polyclonal T cell phenotyping on day 15 post-challenge again showed that blocking IFN-γ before reinfection significantly reduced the fraction of Teff generated during P. chabaudi challenge, and was associated with higher parasitemia, suggesting a role for antigen presentation during challenge that was not tested here (Fig 7K). Here, IFNG is linked to parasitic infectious disease.