Accordingly, a metagenomic analysis showed that the enrichment of Akkermansia muciniphila in faecal samples from non-small cell lung cancer (NSCLC) and renal cell carcinoma (RCC) patients were related to a promising clinical outcome during anti-PD-1 and anti-PD-L1 therapies [189]. The gene discussed is PDCD1; the disease is non-small cell lung carcinoma.