- lncRNA-NEAT1 inhibits proliferation and promotes apoptosis of CML Cells by sponging miR-766-5p. In return, upregulated miR-766-5p reversing the NEAT1 effects on apoptosis and Viability of the CML Cells. The gene discussed is NEAT1; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.