Model 1, which included IL-1β, in addition to sex, age, smoking history, presence/absence of hypertension, D-dimer, white blood cells (WBCs), TC, LDL-C, and HDL-C as independent variables, showed that IL-1β, in addition to D-dimer, was a significant and independent factor associated with the presence of TAAD (odds ratio: 2.04, 95% confidence interval (CI): 1.13–3.71, P=0.019). Here, IL1B is linked to hypertensive disorder.