As strength of TCR signals affects T‐cell differentiation (45) and tumor antigens might often be of low affinity due to their autoantigenic nature (46), low affinity stimulation was initiated using SIITFEKL peptides for OT-1 TCRtg T-cells besides high affinity stimuli (SIINFEKL) with a wide range of concentrations as indicated (Figure 1G). The gene discussed is OXT; the disease is neoplasm.