This approach revealed that TB patients exhibited higher levels of gamma delta T cell, monocyte, M0 macrophage, M1 macrophage, M2 macrophage, activated dendritic cell (DC), and neutrophil abundance, whereas they exhibited fewer naïve CD4+ T cells and follicular helper T (Tfh) cells relative to HC samples (Figure 3A). This evidence concerns the gene CD4 and tuberculosis.