Therefore, we conducted a multi-cytokine panel, including IL-1α, IL-1β, IL-6, IL-10, IL-12p70, IL-17A, IL-23, IL-27, MCP-1, IFN-β, IFN-γ, TNF-α, and GM-CSF to evaluate the level of inflammatory cytokines in the serum of syngeneic mice bearing PD-L1 humanized murine tumor allografts with or without pentamidine or atezolizumab treatment. This evidence concerns the gene CD274 and neoplasm.