Remarkably, human enterocytes with high expression of angiotensin-converting enzyme 2 (ACE2), an entry receptor for SARS-CoV-2, serve as a site of extrapulmonary viral infection as evidenced by the presence of SARS-CoV-2 RNA in faecal samples from COVID-19 patients even after clearance of viral respiratory infection (8, 9). The gene discussed is ACE2; the disease is COVID-19.