IRF8 and diffuse large B-cell lymphoma: The mean IRF8 histoscore and absolute number of positive cells were significantly higher in DLBCL than in lymph node samples (5.2 ± 1.5 vs 3.8 ± 1.6, p= 0.002; and 262.4 ± 134.7 vs 92.6 ± 55.4, p= 1.98E-12, respectively) (Figure 6C).