In DLBCL samples, CD68 expression was significantly and positively correlated with the expression of the key inflammasome markers CASP1, CARD9, TRIM20, GBP1, 3 and 4, NAIP, NLRC4, and NOD2 (0.51≤ R ≤0.75; p ≤0.00028), most of which are part of the canonical inflammasome machinery (GBP1, GBP3, GBP4, CASP1, NAIP, NLRC4, and NOD2) (Figure 2A). This evidence concerns the gene NLRC4 and diffuse large B-cell lymphoma.