Moreover, the Mantel-Cox survival analysis showed that expression of some cytokines and TLRs (CCL19, CCR7, CXCR4, TLR2, and TLR5) was associated with decreased survival (Log10 HR >0.0 and p ≤0.05), while others (CXCL12, CXCL9, IDO1, IL18, IL6, TLR4 and TLR8) were associated with increased survival (Log10 HR <0.0 and p ≤0.05) of patients with DLBCL (Figures S1C-E). The gene discussed is TLR4; the disease is diffuse large B-cell lymphoma.