PKD1 and autosomal dominant polycystic kidney disease: Living kidney donors coming forward from the same family as the recipients with ADPKD need special consideration because of the risk of transplanting a kidney with ADPKD and the risk of late manifestations of ADPKD in the donor.38 The indications for imaging and genetic testing for PKD1 and PKD2 mutations and diagnostic criteria for ADPKD while investigating an LKD from an ADPKD family, where cysts may not be detected in the early years of life, are outlined in the flow diagram (Figure 2 and 4).39,40