In addition, we also examined the correlation between CFL1 and PHGDH using the publicly available dataset (GSE109211).[23] The results show that CFL1 expression is positively correlated with PHGDH expression (Figure 4H), and both of them are highly expressed in the tumor tissues of sorafenib‐insensitive HCC patients compared to sorafenib‐sensitive HCC patients (Figure 4I). This evidence concerns the gene PHGDH and neoplasm.