Furthermore, MST3 interacts with the evolutionarily conserved MO25 scaffolding protein [52], which is the master regulator of the LKB1 (serine-threonine liver kinase B1) tumor suppressor [53], indicating the possibility of MST3 in regulating tumor progression by targeting the MO25-LKB1 pathway. The gene discussed is STK11; the disease is neoplasm.