Enhancer of Zeste Homolog 2 (EZH2) is a core component of Polycomb Repressive Complex 2 (PRC2), which has been reported to play important role in oncogenesis, tumour growth and metastasis in numerous malignant tumours by regulating gene expression through trimethylation of H3K27 [17]. This evidence concerns the gene EZH2 and neoplasm.