We also identified some other variants (TP53 p.Pro3050Leu, TP53 p.Val272Met, TP53 p.Phe270Leu, TP53 p.Arg337Pro, and TP53 p.Ile254Va) in the resistant group that have been previously reported in breast cancer [43, 62, 63]. Here, TP53 is linked to breast cancer.