MUC16 and neoplasm: A Cox univariate analysis showed that age (≤ 60 years vs. > 60 years, P = 0.001), preoperative obstruction (P < 0.001), vascular tumour thrombus (P = 0.032), PNI (P = 0.024), postoperative chemotherapy (P < 0.001), degree of differentiation (poorly vs. moderately, P = 0.003), TNM stage (I vs. IV, P = 0.042), N stage (N0 vs. N1, N2, P < 0.001), M stage (P = 0.001), preoperative complications (P = 0.035), preoperative CEA (< 5 μg/L vs. ≥ 5 μg/L, P < 0.001), CA 19 − 9 (< 37 U/mL vs. ≥ 37 U/mL, P < 0.001), and CA125 level (< 35 U/mL vs. ≥ 35 U/mL, P < 0.001) were the prognostic factors of OS.