A univariate analysis of the Cox regression model showed that preoperative intestinal obstruction (P = 0.025), vascular tumour thrombus (P = 0.002), PNI (P = 0.005), degree of differentiation (poorly vs. moderately, P = 0.003), TNM stage (I vs. IV, P = 0.009), N stage (N0 vs. N1: P = 0.047; N0 vs. N2: P < 0.001), M stage (P < 0.001), preoperative CEA level (< 5 μg/L vs. ≥ 5 μg/L, P < 0.001), Preoperative CA 19 − 9 level (< 37 U/mL vs. ≥ 37 U/mL, P = 0.008), and preoperative CA125 level (< 35 U/mL vs. ≥ 35 U/mL, P = 0.030) were significant prognostic factors for DFS. Here, MUC16 is linked to vascular neoplasm.