In addition, younger age, no preoperative intestinal obstruction, postoperative chemotherapy, presence of venous invasion, higher tumour stage, primary tumour in the rectum, lower ASA score, preoperative neoadjuvant chemotherapy, preoperative comorbidities, preoperative cardiovascular disease, lower preoperative CA125 level, and absence of postoperative intestinal obstruction and surgical site infection were all associated with a significantly increased proportion of postoperative chemotherapy use (P > 0.05). The gene discussed is MUC16; the disease is cardiovascular disorder.