Consequently, the IL-10/IL-12 transcript ratio increased significantly to 270.2 ± 204.8, 211.2 ± 135.6, 312.2 ± 87.7 and 235.7 ± 129.2 (p < 0.05, Table 2) in the macrophages treated with CFS from strains 10A, 11A, CZ103 and UFG121, respectively, compared with untreated control macrophages (9.8 ± 13.4), indicating a potential anti-inflammatory profile for these strains. Here, IL10 is linked to myalgic encephalomeyelitis/chronic fatigue syndrome.