DHCR24 and obesity due to melanocortin 4 receptor deficiency: Because obesity and lipid dysregulation are well-known hallmarks of type 2 diabetes, and because DHCR24 encodes for an enzyme related to the metabolism of cholesterol (3-hydroxysterol-24 reductase) [41], an association between methylation at DHCR24 and type 2 diabetes is plausible.