An analysis of the protein expression data from the CRC set in The Cancer Proteome Atlas (TCPA) and Clinical Proteomic Tumor Analysis Consortium (CPTAC) databases also indicated that FASN was overexpressed in cancer tissue when compared with normal tissue (Supplementary Fig. 5d); again the FASN levels were positively correlated with the levels of CSN6 (Supplementary Fig. 5e). This evidence concerns the gene COPS6 and colorectal carcinoma.